When reaching 25%, 50% and 75%, it produces a negative effect.

25%: Pain

• Fumble Chance: +7.5%
• Healing Efficiency: -15%
• Damage Taken: +10%

50%: Strong Pain

• Will Power: -3.5%
• Fumble Chance: +15%
• Healing Efficiency: -30%
• Sanity Change: -0.05%
• Damage Taken: +20%

75%: Pain Shock

• Will Power: -8.8%
• Fumble Chance: +33%
• Healing Efficiency: -60%
• Sanity Change: -0.10%
• Damage Taken: +30%
• Stumbling: A chance to walk to a random tile when moving.
• Near Death: Every few turns the character’s max health is being reduced.